Within the Ballyharaiws.com website, I have an entire section dedicated to Irish Wolfhound Health Concerns along with Spay Neuter Concerns, in which both contain essential recommendations and precautions all Wolfhound owners should take BEFORE any elective surgery on their Sighthounds. You will find reports about the Greyhound and Scottish Deerhound authored by John Dillberger, DVM on the dangers of Post-Operative bleeding in Sighthounds and the drug that should be administered immediately following any surgery.
In the late 2000s, disproportionate cases of postoperative bleeding were taking place in Greyhounds one or two days after surgery in which affected dogs formed normal blood clots but then dissolved too quickly resulting in early deaths. Foremost, in the Greyhound studies, Blood Clotting Function was tested before surgery, and results were normal as were their Serum Chemistry Profiles and Complete Blood Cell Counts.
Aminocaproic Acid (Amicar) is a drug vital to Sighthounds most often when you least expect it such as after routine spay neuter surgery or more complicated operations in areas prone to more profuse bleeding. The drug prevents or treats delayed postoperative bleeding usually given every 8 hours for five days. Without having taken Amicar, I know of at least two Wolfhounds who, after surgery, one or two-days later "bled out" and died and their blood clotting tests, CBC, etc. were also normal.
According to the report, Gazehounds with high-performance circulatory systems have thick blood moving at high speed and under high pressure. Consequently, they have more frequent blood vessel damage and micro-clot formation. As a consequence these Gazehounds almost certainly have fibrinolysis systems that are hyperactive, putting them at risk for delayed
postoperative bleeding. The clots form but begin to dissolve far too early leaving the hound in jeopardy. Typically, the hound goes home with the owner, but complications begin approximately 24-36 hours later, and hounds have been found dead having bled-out.
The Board Certified veterinarian I spoke with explained that they believe it is a recessive genetic mutation which you CANNOT possibly know exists, regardless if "You have never had it before." Remember, each of your hounds do not inherit the same genes as the other another from each Parent. It is possible that one littermate may inherit such mutation associated with high-performance circulatory systems and another does not but one thing is certain, you can never be sure. Do not risk not using Amicar, otherwise, you could wake up one day to find your beloved companion has died.
Keep foremost in mind that Amicar is a SPECIALTY drug that most veterinary practices do not usually have in stock unless they are a specialty clinic. As such, Amicar MUST be ordered in advance and kept on hand at your local facility in case of an emergency such as Bloat surgery, and it is 3:00 in the morning.